Toxic megacolon, which shows a massively enlarged and distended colon, is definitely a manifestation of serious disease. Severe cases may also be associated with generalized infections leading to instability of blood pressure and heartrate, in addition to disruption of the functions of various other body organs . It isn’t clear why different people have different reactions to C. Difficile infections.. Clostridium Difficile Symptoms The symptoms of C. Difficile colitis range from mild to severe.GeneX is resorbable and is totally replaced by bone completely. Related StoriesInnovative single-make use of torque instruments utilize hard polycarbonate from BayerInnovative single-make use of torque instruments utilize difficult polycarbonate from BayerSpotting the symptoms of advanced prostate cancers: an interview with Brian TomlinsonCommenting on the clearance, Dr Simon Zhou, General Supervisor of Biocomposites Ltd stated ‘ In the fast developing Chinese marketplace, surgeons and patients is now able to make best use of the significant benefits that geneX brings over traditional bone graft substitutes ‘.