Past approaches to developing and scripting the fate of stem cells have involved adding growth-regulating and other substances to cultures of stem cells growing in the laboratory. These circumstances left researchers guessing about exactly what wound up in the stem cells. Kiessling and co-workers are pioneering a new approach that involves using chemically controlled surfaces. Kiessling previously developed chemically modified plastic and glass surfaces that take a lot of the guess workout of growing stem cells in laboratory cultures. In the past, researchers grew stem cells on surfaces that included mouse cells. That left researchers with nagging questions about feasible contamination of stem cells with disease-causing animal viruses – a stumbling block for using stem cells in potential medical applications.This was the 1st time the avian influenza virus got ever been discovered to jump straight from birds to human beings. In this outbreak 18 individuals were hospitalized and 6 passed away. To regulate the outbreak 1.5 million chickens were killed. Since there were other outbreaks in Asia and European countries then. The disease can be spread by the saliva, nasal secretions, and feces of infected pets, which various other animals or humans are exposed to then. The only method to avoid its spread would be to kill the contaminated birds. There are many strains circulating among birds, however the H5N1 strain is infecting individuals who have been in close connection with chickens also.