An initial stage toward increasing the potency of chemotherapy The analysis is promising: chemotherapy coupled with particular PHD2 inhibitors would make chemotherapy far better while reducing the dangerous unwanted effects that place such much burden on patients. However, there are no particular PHD2 inhibitors available at this time, so we have quite a distance to go before individuals will be able to reap the benefits of this discovery..Significant cis-results were also noticed between variants in the HLA area on chromosome 6 and two close by genes HLA-DQA1 and HLA-DQA1. An study of trans-effects revealed 23 DNA sequence variants that reached statistical significance concerning variants from the SNCA, RIT2 and MAPT genes. ‘The identification of the precise changed genes in PD opens possibilities to further research them in model organisms or cell lines with the purpose of identifying drugs which might rectify the defects as treatment for PD,’ stated Myers. This research was funded by the Cogan Family Foundation, the Bumpus Basis and the National Institute of Neurological Disorders and Stroke under award amount PHS-NS076843..